Abnormal proteins called amyloids are strongly implicated in Alzheimer's disease and other deadly diseases. Researchers have not been able to explain how harmless, normal protein sequences go awry and assume the deadly amyloid shape. To study the initial amyloid nucleation, Georgia Tech researchers and their collaborators turned to yeast as a model to study the human amyloids. The researchers successfully applied the method to several proteins, allowing for deeper understanding of abnormal protein aggregation.
Mark E. Hay, Regents Professor and Harry and Linda Teasley Chair in the School of Biological Sciences at Georgia Tech, is the recipient of the 2018 Gilbert Morgan Smith Medal of the National Academy of Sciences. The award recognizes Hay’s research into algal science, with implications for the world’s imperiled coral reefs.
Mud crabs hide for their lives if blue crabs, which prey upon them, pee anywhere near them. Pinpointing urine compounds for the first time that warn the mud crabs of predatory peril initiates a new level of understanding of how chemicals invisibly regulate undersea wildlife and ecosystems.