To test whether the presence of RNA in DNA duplexes could alter the elasticity and structure of DNA, a group of researchers at Georgia Tech and Georgia State University, inspired by Francesca Storici, and including the labs of Elisa Riedo, Angelo Bongiorno and Markus Germann conducted a multidisciplinary study at the interface of physics, chemistry and molecular biology. The group employed atomic force microscopy (AFM)-based single molecule force-measurements of short rNMP(s)-containing oligonucleotides in combination with molecular dynamics (MD) simulations and nuclear magnetic resonance (NMR).
New research reveals how the algae behind red tide thoroughly disables – but doesn’t kill – other species of algae. The study shows how chemical signaling between algae can trigger big changes in the marine ecosystem.
A study of 338 patients with coronary artery disease has identified a gene expression profile associated with an elevated risk of cardiovascular death. Used with other indicators such as biochemical markers and family history, the profile – based on a simple blood test – may help identify patients who could benefit from personalized treatment and counseling designed to address risk factors.
According to a study published in the journal Proceedings of the National Academy of Sciences, co-evolutionary changes in species may reverse traditional predator-prey population cycles, creating the appearance that prey are eating the predators.
Monica’s research will focus on a systems biology approach towards the developing of a malaria vaccine. Using gene expression profiling of the human immune response to malaria vaccination, Monica hopes to investigate the safety and efficacy of vaccines, along with the most effective strategies of vaccine implementation.
Congratulations to the following faculty and staff members who were honored at the 2014 Faculty and Staff Honors Luncheon on April 11.
Fish living on coral reefs where carbon dioxide seeps from the ocean floor were less able to detect predator odor than fish from normal coral reefs, according to a new study.
The study confirms laboratory experiments showing that the behavior of reef fishes can be seriously affected by increased carbon dioxide concentrations in the ocean. The new study is the first to analyze the sensory impairment of fish from CO2 seeps, where pH is similar to what climate models forecast for surface waters by the turn of the century.
From time to time, living cells will accidently make an extra copy of a gene during the normal replication process. Throughout the history of life, evolution has molded some of these seemingly superfluous genes into a source of genetic novelty, adaptation and diversity. A new study shows one way that some duplicate genes could have long-ago escaped elimination from the genome, leading to the genetic innovation seen in modern life.
Jeff Skolnick awarded for fostering excellence in scientific research